OTTAWA — An experimental, made-in-Ottawa virus that attacks tumours has been shown to be a safe and potentially useful drug against hard-to-treat cancers, justifying further trials in more patients.
Early results even raise the possibility that the treatment could actually prevent the spread of tumours — a long-desired goal in the hunt for better cancer therapies.
John Bell, a senior scientist at The Ottawa Hospital Research Institute and University of Ottawa, is working on a cancer-killing virus genetically engineered from a version used to vaccinate against smallpox.
The virus showed signs of quickly infecting and killing cancer cells, while protecting healthy cells, which current therapies can’t do. The virus also appeared as capable of attacking isolated tumours as those spread throughout the body, which are the toughest to treat.